December 1, 1975American Journal of Epidemiology
Epidemiologic Studies of Coronary Heart Disease and Stroke in Japanese Men Living in Japan, Hawaii and California: Introduction1
Key result
Geographic location among 11,900 Japanese men was studied to investigate the observed gradient in coronary heart disease mortality increasing from Japan to Hawaii to California.
Why the study?
Does geographic location (Japan vs Hawaii vs California) affect coronary heart disease and stroke mortality and prevalence among Japanese men?
Population
11,900 Japanese men in Hiroshima and Nagasaki, Japan, Honolulu, Hawaii, and the San Francisco Bay Area of…
Design
Cohort
Authors
Discussion
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Implication
Geographic CHD mortality gradient in Japanese men may reflect environment; leaves open causal mechanisms versus genetics.
Study Design
Type
Observational (n=11,900)
Multicenter
Yes
Structured PICO
Does geographic location (Japan vs Hawaii vs California) affect coronary heart disease and stroke mortality and prevalence among Japanese men?
P
Population
11,900 Japanese men in Hiroshima and Nagasaki, Japan, Honolulu, Hawaii, and the San Francisco Bay Area of California
O
Outcome
Mortality comparisons, biochemical and blood pressure distributions, and heart disease prevalencehard clinical
This paper introduces a large epidemiologic study investigating the environmental and geographic factors contributing to the gradient in CHD mortality among Japanese men across Japan, Hawaii, and California.
Cite This Study
Syme et al. (1975) conducted an observational in Coronary heart disease and stroke (n=11,900). Geographic location was evaluated. Geographic location among 11,900 Japanese men was studied to investigate the observed gradient in coronary heart disease mortality increasing from Japan to Hawaii to California.