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December 1, 1975American Journal of Epidemiology

Epidemiologic Studies of Coronary Heart Disease and Stroke in Japanese Men Living in Japan, Hawaii and California: Mortality1

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Why the study?

Does migration to the United States affect coronary heart disease and stroke mortality in Japanese men?

Population

45-64-year-old Japanese men in Hiroshima and Nagasaki, Honolulu, and the San Francisco area

Comparison

Living in the United States (Hawaii or California) vs Living in Japan

Design

Cohort

Follow-up

1965-1972 (various periods depending on cohort)

Authors

RWRobert M. WorthHKHiroo KatoGRG G Rhoads

Discussion

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Overview

Supports environmental modulation of CVD mortality in Japanese migrants; leaves open specific causal pathways.

Structured PICO

Does migration to the United States affect coronary heart disease and stroke mortality in Japanese men?

P
Population
45-64-year-old Japanese men in Hiroshima and Nagasaki (1965-1970), Honolulu (1966-1970), and the San Francisco area (1968-1972)
I
Intervention
Living in the United States (Hawaii or California)
C
Comparator
Living in Japan
O
Outcome
Stroke, coronary heart disease (CHD), and total mortality evaluated from death certificateshard clinical

Migration of Japanese men to the US is associated with increased CHD mortality but decreased stroke mortality compared to those remaining in Japan, highlighting environmental influences on cardiovascular risk.

Limitations

  • Number of stroke deaths below age 60 too few for analysis

Cite This Study

Worth et al. (1975) studied this question.

synapsesocial.com/papers/6a19b35260e90a7f5fea90d7https://doi.org/10.1093/oxfordjournals.aje.a112186
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