Key result
Atropine injection into ganglionated plexi promoted electrical stimulation-induced focal atrial tachycardia in dogs, with duration increased by adrenergic agonists and terminated by beta blockade.
Population
14 pentobarbital anesthetized dogs
Comparison
Electrical stimulation of the anterior right… vs Baseline electrical stimulation of the ARGP and…
Design
Preclinical
Authors
Loading...
Offers canine model for focal atrial tachycardia via cholinergic blockade; hypothesis-generating for human autonomic triggers, needs clinical validation.
Cholinergic blockade combined with electrical stimulation of ganglionated plexi provides a reproducible experimental model for focal atrial tachycardia that mimics clinical localization.
Liu et al. (2013) studied Focal atrial tachycardia (n=14). Electrical stimulation of ganglionated plexi with atropine injection vs. Baseline electrical stimulation was evaluated on Induction of atrial tachycardia. Atropine injection into ganglionated plexi promoted electrical stimulation-induced focal atrial tachycardia in dogs, with duration increased by adrenergic agonists and terminated by beta blockade.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: