Why the study?
Does amiodarone prevent spontaneous recurrence in patients with recurrent ventricular tachycardia or ventricular fibrillation?
Population
45 patients with recurrent ventricular tachycardia (n=29) or ventricular fibrillation (n=16)
Design
Cohort
Follow-up
mean 12.7 +/- 8.8 months (range, 3 to 36)
Authors
Discussion
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Member takes
Implication
Amiodarone may reduce recurrences in refractory VT/VF; this Level 3 cohort finding leaves open the need for randomized confirmation.
Structured PICO
Does amiodarone prevent spontaneous recurrence in patients with recurrent ventricular tachycardia or ventricular fibrillation?
P
Population
45 patients with recurrent ventricular tachycardia (n=29) or ventricular fibrillation (n=16)
I
Intervention
Amiodarone (doses up to 2000 mg a day evaluated)
O
Outcome
Success of therapy (prevention of spontaneous recurrence of ventricular tachycardia or ventricular fibrillation)hard clinical
Amiodarone is effective for long-term therapy of recurrent ventricular tachyarrhythmias, and induction of arrhythmia during therapy does not always predict clinical efficacy.
Cite This Study
Heger et al. (1981) studied this question.