Key result
Sudden cardiac death accounts for approximately 50% of the 10% to 50% annual mortality risk in patients with heart failure, necessitating effective risk stratification and therapeutic interventions.
This review outlines the risk stratification, pathophysiology, and therapeutic interventions for sudden cardiac death in patients with chronic heart failure, alongside counseling and resuscitative issues.
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Alerts clinicians to SCD burden in HF; leaves open optimal risk stratification and targeted therapies.
Chronic heart failure (HF) and sudden cardiac death (SCD) present two major public health problems. The risk of death ranges from 10% to 50% annually in patients with HF, depending on the severity of disease. Approximately 50% of these deaths are sudden and presumed to be caused by dysrhythmias. This article defines the population at risk for SCD, explains the methods used for risk stratification, reviews current research on the pathophysiology of ventricular dysrhythmias in HF, and discusses pertinent clinical trials of therapeutic interventions on SCD in HF. The article also explores the effect of SCD on the patient and family with respect to counseling and education, resuscitative issues, and advanced directives.
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Tedesco et al. (2000) conducted a review in Heart failure. Sudden cardiac death accounts for approximately 50% of the 10% to 50% annual mortality risk in patients with heart failure, necessitating effective risk stratification and therapeutic interventions.
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