Key result
Endemic foot-and-mouth disease in Ethiopia drives significant economic losses necessitating continuous surveillance for vaccine matching.
Why the study?
To provide a comprehensive overview of the molecular epidemiology, economic impact, diagnosis, and control measures of foot-and-mouth disease in Ethiopia compared with the global situation.
FMD is a major endemic disease in Ethiopia with significant economic impact, necessitating continuous molecular surveillance for effective vaccine matching.
Answers are grounded in this paper and cite their sources.
May inform livestock control in endemic regions; leaves open prospective validation of surveillance-driven vaccine strategies.
Foot-and-mouth disease (FMD) is a contagious viral disease that affects the livelihoods and productivity of livestock farmers in endemic regions. It can infect various domestic and wild animals with cloven hooves and is caused by a virus belonging to the genus Aphthovirus and family Picornaviridae, which has seven different serotypes: A, O, C, SAT1, SAT2, SAT3, and Asia-1. This paper aims to provide a comprehensive overview of the molecular epidemiology, economic impact, diagnosis, and control measures of FMD in Ethiopia in comparison with the global situation. The genetic and antigenic diversity of FMD viruses requires a thorough understanding for developing and applying effective control strategies in endemic areas. FMD has direct and indirect economic consequences on animal production. In Ethiopia, FMD outbreaks have led to millions of USD losses due to the restriction or rejection of livestock products in the international market. Therefore, in endemic areas, disease control depends on vaccinations to prevent animals from developing clinical disease. However, in Ethiopia, due to the presence of diverse antigenic serotypes of FMD viruses, regular and extensive molecular investigation of new field isolates is necessary to perform vaccine-matching studies to evaluate the protective potential of the vaccine strain in the country.
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Zewdie et al. (2023) conducted a review in Foot-and-mouth disease (FMD). Foot-and-mouth disease is highly endemic in Ethiopia, with multiple circulating serotypes causing significant economic losses and necessitating continuous molecular surveillance for effective vaccine matching.
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