Why the study?
Does stretching affect conduction velocity differently in Purkinje fibers from adult versus 8-week-old dogs?
Population
Purkinje fiber bundles from adult and 8-week-old dogs
Comparison
Stretching of fiber bundles vs Control length and comparison between adult and…
Design
Preclinical
Authors
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Maturation increases Purkinje fiber conduction velocity in dogs independent of stretch; leaves open relevance to human conduction system development.
Does stretching affect conduction velocity differently in Purkinje fibers from adult versus 8-week-old dogs?
Structural changes in cardiac Purkinje fibers explain conduction velocity changes with stretch, which remains faster in adult compared to young dogs at all degrees of stretch.
Rosen et al. (1981) studied this question.
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