Why the study?
Does primary percutaneous coronary intervention performed during off-hours compared to on-hours worsen clinical outcomes in patients with ST elevation myocardial infarction?
Population
1,108 consecutive patients with ST elevation myocardial infarction (STEMI)
Comparison
Primary percutaneous coronary intervention… vs Primary percutaneous coronary intervention…
Design
Cohort
Follow-up
1 year
Key result
Primary percutaneous coronary intervention during off-hours resulted in similar in-hospital mortality compared to on-hours (10.2% vs 7.6%; p=0.16), despite longer door-to-balloon times.
Authors
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Off-hours primary PCI was associated with similar mortality despite delays; leaves open whether system improvements can optimize STEMI workflows.
Cohort (n=1,108)
No
Does primary percutaneous coronary intervention performed during off-hours compared to on-hours worsen clinical outcomes in patients with ST elevation myocardial infarction?
Absolute Event Rate: 10.2% vs 7.6%
p-value: p=0.16
Primary PCI for STEMI performed during off-hours is associated with longer door-to-balloon times but similar in-hospital and 1-year mortality compared to procedures performed during regular working hours.
Cardoso et al. (2014) conducted a cohort in ST elevation myocardial infarction (n=1,108). Primary percutaneous coronary intervention during off-hours vs. Primary percutaneous coronary intervention during on-hours was evaluated on In-hospital mortality (p=0.16). Primary percutaneous coronary intervention during off-hours resulted in similar in-hospital mortality compared to on-hours (10.2% vs 7.6%; p=0.16), despite longer door-to-balloon times.