Why the study?
Does primary percutaneous coronary intervention performed during off-hours worsen mortality in patients with ST elevation myocardial infarction compared to on-hours?
Population
1,108 consecutive patients with ST elevation myocardial infarction (STEMI)
Comparison
Primary percutaneous coronary intervention… vs Primary percutaneous coronary intervention…
Design
Cohort
Follow-up
1 year
Key result
Primary percutaneous coronary intervention during off-hours yielded similar in-hospital mortality to on-hours (10.2% vs 7.6%; P=0.16), although door-to-balloon time was significantly longer.
Authors
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Off-hours primary PCI was associated with similar mortality despite delays; leaves open whether door-to-balloon optimization improves outcomes in prospective cohorts.
Cohort (n=1,108)
No
Does primary percutaneous coronary intervention performed during off-hours worsen mortality in patients with ST elevation myocardial infarction compared to on-hours?
Absolute Event Rate: 10.2% vs 7.6%
p-value: p=0.16
Although off-hours primary PCI for STEMI is associated with longer door-to-balloon times, it does not significantly increase in-hospital or 1-year mortality compared to on-hours PCI.
Cardoso et al. (2014) conducted a cohort in ST elevation myocardial infarction (n=1,108). Primary percutaneous coronary intervention during off-hours vs. Primary percutaneous coronary intervention during on-hours was evaluated on In-hospital mortality (p=0.16). Primary percutaneous coronary intervention during off-hours yielded similar in-hospital mortality to on-hours (10.2% vs 7.6%; P=0.16), although door-to-balloon time was significantly longer.