May 1, 2002Diabetes
Associations of Insulin Levels With Left Ventricular Structure and Function in American Indians
Why the study?
Are fasting insulin levels associated with left ventricular structure and function in nondiabetic American Indians?
Population
1,388 nondiabetic American Indian participants (45% men) in the Strong Heart Study (SHS)
Comparison
Fasting insulin levels vs Normal fasting insulin levels
Design
Cross-sectional
Authors
Discussion
Loading...
Member takes
Implication
Should not change practice; hypothesis-generating for sex-specific insulin-LV associations in nondiabetic populations.
Structured PICO
Are fasting insulin levels associated with left ventricular structure and function in nondiabetic American Indians?
P
Population
1,388 nondiabetic American Indian participants (45% men) in the Strong Heart Study (SHS)
I
Intervention
Fasting insulin levels (evaluated continuously and as elevated vs. normal)
C
Comparator
Normal fasting insulin levels
O
Outcome
Echocardiographic left ventricular measurements (LV mass, left atrial diameter, posterior wall thickness, septal thickness, LV diameter, cardiac output, relative wall thickness, peripheral resistance)surrogate
In nondiabetic American Indians, higher fasting insulin levels are associated with greater LV size and cardiac output in men, and more concentric LV geometry in women, independent of body size.
Cite This Study
Ilercil et al. (2002) studied this question.