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January 1, 2008GerontologyOpen Access

The Aging Cardiomyocyte: A Mini-Review

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Key result

Physiological aging of the heart and cardiomyocytes is primarily driven by intrinsic aging factors, while extrinsic factors like smoking contribute to pathologically accelerated aging.

Population

Aging cardiomyocytes and the aging heart

Design

Review

Authors

DBDavid BernhardJohannes Kepler University of LinzGLGünther LauferCardiac Surgery

Discussion

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Implication

Distinguishes intrinsic from extrinsic cardiac aging drivers; hypothesis-generating for prevention trials before clinical adoption.

Structured PICO

P
Population
Aging cardiomyocytes and the aging heart

This review highlights that intrinsic factors primarily drive physiological cardiomyocyte aging, while extrinsic factors accelerate pathological aging.

Cite This Study

Bernhard et al. (2008) conducted a review in Aging of cardiomyocytes. Physiological aging of the heart and cardiomyocytes is primarily driven by intrinsic aging factors, while extrinsic factors like smoking contribute to pathologically accelerated aging.

synapsesocial.com/papers/6a121bbc45487b7639a5e5c2https://doi.org/10.1159/000113503
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