Key result
New device-specific percentile curves establish increasing aortic PWV with age in healthy individuals under 40.
Why the study?
To identify young people at increased cardiovascular disease risk using aortic pulse wave velocity, reference values needed to be determined.
Population
19 930 healthy participants aged 1 to 40 years
Design
Retrospective, multicenter study
Authors
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May aid identification of early vascular aging in youth; leaves open prospective outcome validation across devices.
Observational (n=19,930)
Yes
This study establishes device-specific reference values for aortic pulse wave velocity in healthy youth, enabling the clinical identification of impaired vascular aging and future cardiovascular risk.
Kodithuwakku et al. (2025) conducted an observational in Healthy (n=19,930). Aortic pulse wave velocity (PWV) measurement was evaluated on Device-specific percentile curves for aortic PWV. Reference values and device-specific percentile curves for aortic pulse wave velocity were established for 19,930 healthy individuals aged 1 to 40 years, showing an increasing trend with age.
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