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October 9, 2008Journal of Hypertension

Reference values of aortic pulse wave velocity in the elderly

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Key result

Aortic pulse wave velocity averaged 8.7 m/s in healthy elderly individuals aged 60-75 years compared to 10.2 m/s in those with hypertension or diabetes (P<0.0001).

Population

455 community-living ambulatory individuals aged 60-75 years, divided into a 'reference-values group' and a…

Design

Cross-sectional

Authors

CACosmin AlecuCentre National de la Recherche ScientifiqueCLCarlos LabatVascular / Pulmonary VascularAKAnna Kearney‐SchwartzInserm

Discussion

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Implication

May support PWV reference values in healthy elderly; leaves open prospective outcome validation before clinical adoption.

Study Design

Type

Cross-Sectional (n=455)

Structured PICO

P
Population
455 community-living ambulatory individuals aged 60-75 years, divided into a 'reference-values group' (n=206, without hypertension or diabetes) and a 'hypertension-diabetes group' (n=249, with hypertension or diabetes).
I
Intervention
Assessment of aortic pulse wave velocity (AoPWV) using applanation tonometry (PulsePen device)
O
Outcome
Reference values for aortic pulse wave velocity (AoPWV)surrogate

Main Result

Absolute Event Rate: 8.7% vs 10.2%

p-value: p=<0.0001

In elderly individuals aged 60-75 years, an aortic pulse wave velocity below 10 m/s can be considered normal, 10-13 m/s as borderline, and above 13 m/s as elevated.

Cite This Study

Alecu et al. (2008) conducted a cross-sectional in Community living ambulatory elderly (n=455). Aortic pulse wave velocity assessment vs. Individuals with hypertension or diabetes was evaluated on Mean aortic pulse wave velocity (p=<0.0001). Aortic pulse wave velocity averaged 8.7 m/s in healthy elderly individuals aged 60-75 years compared to 10.2 m/s in those with hypertension or diabetes (P<0.0001).

synapsesocial.com/papers/6a11f07a16bc81049accbfd2https://doi.org/10.1097/hjh.0b013e32830e4932

Topics

Hypertension management
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