Impact of home and clinical blood pressure variability on arteriosclerosis and metabolic indicators: a prospective multicenter registry study

Fig. 1. Study flowchart. BP, blood pressure.

Fig. 2. Correlation heatmap of home and office BP metrics. (A) shows correlations between home and office SBP metrics, (B) shows correlations between home and office DBP metrics. Each cell displays the Pearson correlation coefficient (r) and the corresponding P-value for the association between six home and office BP metrics (mean, SD, CV, ARV, VIM, range). The color scale ranges from −1.0 (blue) to +1.0 (red), with white indicating no correlation. BP, blood pressure; SBP, systolic blood pressure; DBP, diastolic blood pressure; SD, standard deviation; CV, coefficient of variation; ARV, average real variability; VIM, variability independent of the mean.

Fig. 3. Correlation heatmap of home BP metrics and metabolic parameters. (A) shows correlations between home SBP metrics and metabolic parameters, (B) shows correlations between home DBP metrics and metabolic parameters. Each cell displays the Pearson correlation coefficient (r) and the corresponding P-value for the association between six home blood pressure metrics (mean, SD, CV, ARV, VIM, range) and six metabolic parameters (total cholesterol, LDL-C, HDL-C, triglycerides, glucose, hs-CRP). The color scale ranges from −1.0 (blue) to +1.0 (red), with white indicating no correlation. BP, blood pressure; SBP, systolic blood pressure; DBP, diastolic blood pressure; SD, standard deviation; CV, coefficient of variation; ARV, average real variability; VIM, variability independent of the mean; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; hs-CRP, high sensitivity C-reactive protein.

Fig. 4. Correlation heatmap of home BP metrics and arterial stiffness parameters. (A) shows correlations between home SBP metrics and arterial stiffness parameters, (B) shows correlations between home DBP metrics and arterial stiffness parameters. Each cell displays the Pearson correlation coefficient (r) and the corresponding P-value for the association between six home BP metrics (mean, SD, CV, VIM, ARV, range) and five arterial stiffness parameters (SBP2, cSBP, AIp75, ABI, baPWV). The color scale ranges from −1.0 (blue) to +1.0 (red), with white indicating no correlation. BP, blood pressure; SBP, systolic blood pressure; DBP, diastolic blood pressure; SD, standard deviation; CV, coefficient of variation; VIM, variability independent of the mean; ARV, average real variability; SBP2, second systolic peak; cSBP, central systolic blood pressure; AIp75, augmentation index adjusted to a heart rate of 75 bpm; ABI, ankle-brachial index; baPWV, brachial-ankle pulse wave velocity.