Key result
Tissue Doppler imaging and gadolinium-enhanced magnetic resonance successfully delineated cardiac amyloidosis, matching biopsy-confirmed perivascular amyloid deposits.
Case Report (n=1)
May aid noninvasive cardiac amyloidosis detection; leaves open validation in larger prospective cohorts.
A 64-year-old female presented with biventricular heart failure. Echocardiography revealed features suggestive of amyloidosis, including segmental impairment of longitudinal strain (rate) in the septal and anterior segments, which matched delayed gadolinium-enhanced cardiac magnetic resonance. Guided endomyocardial biopsy confirmed the presence of perivascular amyloid deposits. Tissue Doppler and gadolinium-enhanced magnetic resonance may be helpful in delineating cardiac amyloidosis.
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Smedema et al. (2009) conducted a case report in Primary cardiac amyloidosis (n=1). Tissue Doppler imaging and contrast-enhanced cardiac magnetic resonance was evaluated on Diagnosis of cardiac amyloidosis. Tissue Doppler imaging and gadolinium-enhanced magnetic resonance successfully delineated cardiac amyloidosis, matching biopsy-confirmed perivascular amyloid deposits.