Key result
Patients with suspected CAD exhibit ~28% lower VO2 during treadmill testing versus healthy controls.
Why the study?
Quantifying exercise stress using VO2 and anaerobic threshold during treadmill testing may provide additional insight into the severity of coronary blockages and help predict cardiovascular events.
Does measuring oxygen consumption and anaerobic threshold during conventional treadmill testing differentiate patients with suspected CAD from healthy controls?
Population
100 patients aged 40 to 70 years with suspected CAD and 50 age- and sex-matched healthy controls
Comparison
Patients with suspected CAD vs healthy controls
Design
Case-control study
Authors
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VO2 during treadmill testing was associated with suspected CAD; leaves open whether it enhances differentiation beyond standard protocols.
Case-Control (n=150)
No
Does measuring oxygen consumption and anaerobic threshold during conventional treadmill testing differentiate patients with suspected CAD from healthy controls?
Absolute Event Rate: 20.5% vs 28.6%
p-value: p=<0.01
Measuring oxygen consumption and anaerobic threshold during conventional treadmill testing can enhance the assessment of cardiovascular stress and help detect suspected coronary artery disease.
Waghmare et al. (2025) conducted a case-control in Suspected Coronary Artery Disease (n=150). Conventional treadmill stress test vs. Healthy controls was evaluated on Mean oxygen consumption (VO2) in ml/kg/min (p=<0.01). Patients with suspected coronary artery disease exhibited significantly lower mean oxygen consumption (20.5 vs 28.6 ml/kg/min) during treadmill testing compared to healthy controls.
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