Key result
Chest radiotherapy increases the absolute risk of cardiac morbidity and death by 2% at 5 years and 23% at 20 years compared with nonirradiated patients.
Provides a practical guide to the diagnosis and management of radiation-induced heart disease, highlighting the gap between imaging guidelines and clinical practice.
May support extended cardiac monitoring after chest radiotherapy; leaves open optimal screening and prevention strategies.
Radiation-induced heart disease (RIHD) is a recognized late sequela of chest radiotherapy for conditions such as breast cancer and lymphoma and can involve any cardiac structure. Consensus guidelines from the European Association of Cardiovascular Imaging and the American Society of Echocardiography stress the importance of regular screening for the cardiac effects of radiotherapy. However, a gulf remains between these guidelines and clinical practice.
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Donnellan et al. (2016) conducted a review in Radiation-induced heart disease. Chest radiotherapy vs. No radiotherapy was evaluated. Chest radiotherapy increases the absolute risk of cardiac morbidity and death by 2% at 5 years and 23% at 20 years compared with nonirradiated patients.
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