Key result
Single gap junction channel conductance between fibroblasts was ~21 pS, between myocytes ~18 pS and 43 pS, and in heterologous myocyte-fibroblast junctions ~32 pS, suggesting two gap junction proteins.
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Supports distinct coupling in myocyte-fibroblast pairs; leaves open the second cardiac gap junction protein for targeted study.
Rook et al. (1992) studied Neonatal rat heart cells. Single gap junction channel conductance between fibroblasts was ~21 pS, between myocytes ~18 pS and 43 pS, and in heterologous myocyte-fibroblast junctions ~32 pS, suggesting two gap junction proteins.
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