Key result
Direct electrical coupling between cardiac myocytes and fibroblasts occurs in normal cardiac tissue, suggesting an active contribution of non-myocytes to cardiac electrophysiology.
This review highlights the functional integration of cardiac myocytes and fibroblasts, suggesting that non-myocytes actively contribute to cardiac electrophysiology in both normal and pathological states.
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Challenges myocyte isolation consensus; leaves open whether fibroblast coupling affects arrhythmia risk or management.
Camelliti et al. (2006) conducted a review in Cardiac electrophysiology. Direct electrical coupling between cardiac myocytes and fibroblasts occurs in normal cardiac tissue, suggesting an active contribution of non-myocytes to cardiac electrophysiology.
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