Key result
Diabetes mellitus increased the risk of heart failure re-admission after primary PCI for STEMI compared to no diabetes (HR 1.95 for non-insulin-treated; HR 3.09 for insulin-treated).
Why the study?
Does diabetes mellitus increase the risk of re-admission for heart failure in STEMI patients treated with primary PCI?
Cohort (n=958)
Does diabetes mellitus increase the risk of re-admission for heart failure in STEMI patients treated with primary PCI?
Effect estimate: HR 1.95 (non-insulin-treated), HR 3.09 (insulin-treated) (95% CI 1.30-2.93 (non-insulin-treated), 1.71-5.60 (insulin-treated))
Absolute Event Rate: 15.2% vs 8.4%
Diabetes mellitus, particularly when insulin-treated, independently increases the risk of heart failure readmission in STEMI patients undergoing primary PCI.
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Supports intensified post-PCI HF surveillance in diabetic STEMI patients; extends observational data but leaves causal effects open.
Massalha et al. (2015) conducted a cohort in ST-elevation myocardial infarction (n=958). Diabetes mellitus (non-insulin-treated and insulin-treated) vs. No diabetes mellitus was evaluated on re-admission for heart failure (HR 1.95 (non-insulin-treated), HR 3.09 (insulin-treated), 95% CI 1.30-2.93 (non-insulin-treated), 1.71-5.60 (insulin-treated)). Diabetes mellitus increased the risk of heart failure re-admission after primary PCI for STEMI compared to no diabetes (HR 1.95 for non-insulin-treated; HR 3.09 for insulin-treated).
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