What question did this study set out to answer?

To assess the prescribing frequency, clinical indications, and discharge continuation rates of acid-suppressive medications in hospitalized general medical patients.

November 1, 2000The American Journal of Gastroenterology

Overuse of acid-suppressive therapy in hospitalized patients1

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Authors

RNRobert J. NardinoUniversity of Connecticut RVRonald J. VenderYale New Haven Hospital PHPeter N. HerbertInternational Wildlife Consultants (United Kingdom)

Discussion

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Implication

Observational chart review reveals widespread non-indicated acid-suppressive therapy in hospitalized medical patients, highlighting frequent unnecessary continuation at hospital discharge.

Key Points

To assess the prescribing frequency, clinical indications, and discharge continuation rates of acid-suppressive medications in hospitalized general medical patients.
Conducted a chart review of 226 consecutive patients admitted to a general medical nursing unit at an urban, community, teaching hospital.
Evaluated the timing, drug class (histamine-2 receptor antagonists, proton pump inhibitors, and mucosal barrier agents including famotidine, omeprazole, and sucralfate), and clinical indications via consensus review.
Overall, 54% of hospitalized patients received acid-suppressive therapy, with histamine-2 receptor antagonists being the most frequently prescribed class (62%).
Consensus evaluation revealed that 65% of all acid-suppressive prescriptions lacked an appropriate medical indication.
Among patients initiated on acid-suppressive therapy specifically for stress ulcer prophylaxis, 55% were discharged on the medication.

Cite This Study

Nardino et al. (2000) studied this question.

synapsesocial.com/papers/6a126a19ea48cb855a34cbd0 https://doi.org/10.1111/j.1572-0241.2000.03259.x

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November 1, 2000The American Journal of Gastroenterology

Overuse of acid-suppressive therapy in hospitalized patients1

View Full Paper

Ask AI

Bookmark

Authors

RNRobert J. NardinoUniversity of Connecticut RVRonald J. VenderYale New Haven Hospital PHPeter N. HerbertInternational Wildlife Consultants (United Kingdom)

Discussion

Member takes

Implication

Observational chart review reveals widespread non-indicated acid-suppressive therapy in hospitalized medical patients, highlighting frequent unnecessary continuation at hospital discharge.

Key Points

To assess the prescribing frequency, clinical indications, and discharge continuation rates of acid-suppressive medications in hospitalized general medical patients.
Conducted a chart review of 226 consecutive patients admitted to a general medical nursing unit at an urban, community, teaching hospital.
Evaluated the timing, drug class (histamine-2 receptor antagonists, proton pump inhibitors, and mucosal barrier agents including famotidine, omeprazole, and sucralfate), and clinical indications via consensus review.
Overall, 54% of hospitalized patients received acid-suppressive therapy, with histamine-2 receptor antagonists being the most frequently prescribed class (62%).
Consensus evaluation revealed that 65% of all acid-suppressive prescriptions lacked an appropriate medical indication.
Among patients initiated on acid-suppressive therapy specifically for stress ulcer prophylaxis, 55% were discharged on the medication.

Cite This Study

Nardino et al. (2000) studied this question.

synapsesocial.com/papers/6a126a19ea48cb855a34cbd0 https://doi.org/10.1111/j.1572-0241.2000.03259.x

Also Consider

Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context:

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