Key result
Systematic review protocol outlines methodology to evaluate survival and prognostic indicators in heart failure.
Why the study?
Heart failure requires early symptom identification and management to improve survival, and updated evidence is needed to assess survival rates, prognostic indicators, and the impact of treatment advancements over time.
Systematic Review
This protocol outlines a systematic review and meta-analysis to evaluate the survival rates and prognostic indicators of patients with heart failure globally.
May update global HF survival estimates for clinicians; extends prior prognostic syntheses once completed.
Introduction: Heart failure (HF) is a chronic syndrome that necessitates patients' active management of symptoms and adherence to a complex medication regimen. Identifying and treating symptoms early are crucial components of heart failure care, aiming to enhance quality of life and reduce the risk of hospitalization and mortality. Methods and analysis: This review included observational studies or studies that incorporated both interventional and observational phases. Three independent reviewers will search multiple databases, including PubMed, Web of Science, and Scopus. There was no geographical restriction, and the languages of the studies were written in English. The studies were published from August 2018 to August 2023. Three independent reviewers will carry out the literature screening, research selection, and data extraction. Stata 17.0 software was used to construct a funnel map, assess heterogeneity, perform subgroup analysis, and complete sensitivity analysis. Ethics and dissemination: This systematic review aimed to present the most recent findings regarding the survival rates and prognostic indicators of individuals with HF. By comparing outcomes over time, we seek to gain insights into the influence of evidence-based treatment advancements on the average survival of patients. The outcomes of this review are expected to be advantageous for various stakeholders, such as patient advocacy groups, the medical community, policymakers, and researchers. PROSPERO registration number: CRD42023456390
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Norouzi et al. (2024) conducted a systematic review in Heart failure. This systematic review and meta-analysis protocol outlines the methodology to evaluate survival rates and prognostic indicators in patients aged 15 years or older with heart failure.
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