Key result
Metabolic syndrome was associated with significantly higher percent coronary plaque volume compared to subjects without metabolic syndrome (31% vs 21%, p<0.0001) on intravascular ultrasound.
Why the study?
Does metabolic syndrome associate with increased early stage coronary atherosclerosis measured by IVUS in subjects with angiographically normal coronary arteries?
Observational (n=70)
Does metabolic syndrome associate with increased early stage coronary atherosclerosis measured by IVUS in subjects with angiographically normal coronary arteries?
Absolute Event Rate: 31% vs 21%
p-value: p=<0.0001
Metabolic syndrome and hypoadiponectinemia are associated with increased early-stage coronary atherosclerosis and abnormal plaque characteristics even in angiographically normal coronary arteries.
No takes yet. Share an insight, caveat, or question.
Metabolic syndrome may flag subclinical plaque despite normal angiography; leaves open whether targeted therapy alters progression.
Hitsumoto et al. (2007) conducted an observational in Early stage coronary atherosclerosis (n=70). Metabolic syndrome vs. Without metabolic syndrome was evaluated on Percent plaque volume (p=<0.0001). Metabolic syndrome was associated with significantly higher percent coronary plaque volume compared to subjects without metabolic syndrome (31% vs 21%, p<0.0001) on intravascular ultrasound.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: