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April 27, 2005Journal of VirologyOpen Access

Comparative Genomics of Foot-and-Mouth Disease Virus

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Key result

Comparative genomic analysis of 103 foot-and-mouth disease virus isolates revealed highly conserved genomic regions, invariant motifs, and phylogenetic incongruities suggestive of recombination.

Population

103 isolates of foot-and-mouth disease virus (FMDV) representing all seven serotypes

Design

Preclinical

Authors

CCC. CarrilloInstituto Superior Tecnológico LojaETE. R. TulmanUniversity of ConnecticutGDGustavo DelhonUniversity of Nebraska–Lincoln

Discussion

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Implication

Conserved FMDV regions may guide control strategies; leaves open recombination's role in diversity and emergence.

Structured PICO

P
Population
103 isolates of foot-and-mouth disease virus (FMDV) representing all seven serotypes
I
Intervention
Comparative genomic analysis
O
Outcome
Identification of conserved genomic regions, invariant motifs, and phylogenetic incongruities

Comparative genomic analysis of 103 FMDV isolates reveals highly conserved genomic regions and evidence of interserotypic recombination, providing insights into viral biology and genetic diversity.

Cite This Study

Carrillo et al. (2005) studied Foot-and-mouth disease virus (n=103). Comparative genomic analysis of 103 foot-and-mouth disease virus isolates revealed highly conserved genomic regions, invariant motifs, and phylogenetic incongruities suggestive of recombination.

synapsesocial.com/papers/6a127dfb45487b7639a69880https://doi.org/10.1128/jvi.79.10.6487-6504.2005
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