Why the study?
Does CPAP therapy improve cardiac autonomic function as measured by novel respiration-adjusted spectral indices of heart rate variability in patients with obstructive sleep apnea?
Does CPAP therapy improve cardiac autonomic function as measured by novel respiration-adjusted spectral indices of heart rate variability in patients with obstructive sleep apnea?
Respiration-adjusted spectral indices of heart rate variability (MLHR and GRSA) are more sensitive than standard measures in detecting autonomic improvements from CPAP therapy in patients with obstructive sleep apnea.
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Novel respiration-adjusted HRV indices may detect CPAP autonomic effects in OSA missed by standard measures; hypothesis-generating and requires validation before clinical adoption.
Khoo et al. (1999) studied this question.
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