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May 24, 2026Advances in Radiation OncologyOpen Access

Critical Review of Cataractogenesis and Lens Contouring in Radiation Oncology

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Authors

AGAlexander GrosingerARAnna RooversKBKyra M. Boorsma Bergerud

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Overview

Critical review outlines cataract risk factors and proposes standardized lens contouring for better radiotherapy outcomes.

Key Points

  • This review aims to analyze radiation-induced cataractogenesis and propose unified lens contouring guidelines.
  • Conducted a comprehensive literature review on the lens's anatomical and physiological aspects.
  • Reviewed studies on radiation-induced cataracts, their thresholds, latency, and classification systems.
  • Developed standardized contouring guidelines for radiotherapy treatment and dose reporting.
  • Radiation-induced cataracts most commonly present as posterior subcapsular cataracts.
  • Key risk factors include total dose, fractionation, and dose rate.
  • Scheimpflug tomography presents a potential improvement over traditional assessment tools.

Cite This Study

Grosinger et al. (2026) studied this question.

synapsesocial.com/papers/6a1295f648a0ea1665672493https://doi.org/10.1016/j.adro.2026.102100
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