Key result
Obesity induces insulin resistance, and inflammation may be the common mediator linking obesity to the pathogenesis of type 2 diabetes.
This review highlights that inflammation may be the key mediator linking obesity-induced insulin resistance to the development of type 2 diabetes.
Answers are grounded in this paper and cite their sources.
Hypothesis-generating for inflammation as mediator in obesity-diabetes; prospective trials needed before clinical adoption.
The aim of this article was to review the relationship between type 2 diabetes and obesity. The most important environmental risk factors in most patients who develop type 2 diabetes were high caloric intake, decreased physical activity, family history and stronger multiple genetic predisposition. Obesity induces insulin resistance and its mechanism is poorly understood. Inflammation may be the common mediator linking obesity to the pathogenesis of diabetes.
No takes yet. Share an insight, caveat, or question.
Hemanth Kumar B (2013) conducted a review in Type 2 Diabetes and obesity. Obesity induces insulin resistance, and inflammation may be the common mediator linking obesity to the pathogenesis of type 2 diabetes.
Synapse has enriched 10 related papers. Consider them for comparative context: