Key result
Higher Gensini score linked to ~6% greater erectile dysfunction risk per unit in CCS.
Why the study?
The relationship and correlation between Gensini score, which evaluates the extent and severity of CCS, and erectile dysfunction severity had not been investigated.
Is there a relationship between the severity of chronic coronary syndrome (assessed by Gensini score) and erectile dysfunction?
Observational (n=142)
No
Is there a relationship between the severity of chronic coronary syndrome (assessed by Gensini score) and erectile dysfunction?
In male patients with chronic coronary syndrome, higher Gensini scores are significantly associated with increased severity and occurrence of erectile dysfunction.
Answers are grounded in this paper and cite their sources.
May warrant ED assessment in higher Gensini patients; cross-sectional data leaves open causality and practice change.
INTRODUCTION: In previous studies, the relationship between atherosclerosis and erectile dysfunction (ED) was examined, but the relationship and correlation between Gensini score which evaluates the extent and severity of chronic coronary syndrome (CCS), and ED severity were not investigated. AIM: To evaluate the relationship between Gensini score and ED in patients with CCS. METHODS: We included 142 consecutive male patients with the diagnosed CCS and underwent an elective coronary angiography between January 2019 and March 2020. MAIN OUTCOME MEASURE: Correlation analysis demonstrated that Gensini score significantly negatively correlated with the International Index Erectile Function - 5 (IIEF-5) score (r = -0.417, P < .001). RESULTS: Severe ED was present in 48 (33.8%) patients, moderate ED in 31 (21.8%) patients, and mild ED in 22 (15.5%) patients. 41(28.9%) patients did not have ED. Both the No ED and Mild ED groups were statistically significantly lower than the Severe ED group in terms of the Gensini score (P < .05). When the recommended optimal cut-off point and accuracy measurements were made for the Gensini score, the area under curve (AUC) value in predicting ED was 0.806 (95% CI: 0.732-0.880, P < .001). Multivariate logistic regression analysis demonstrated that independent predictors for ED were Gensini score and age (P < .001, and P = .026, respectively). Every 1 unit increase in Gensini score resulted in a 6% increase in the occurrence of ED (OR = 1.06, CI:1.03-1.10, P < .001). CONCLUSION: ED can be caused by endothelial dysfunction. Patients with severe CSS and high Gensini score should be evaluted for ED. ED may be a sign of severe CCS and a high Gensini score. It is also necessary to evaluate cardiological in patients with ED. Deger M, Ozmen C, Akdogan N, et al. The Relationship Between Gensini Score and Erectile Dysfunction in Patients with Chronic Coronary Syndrome. Sex Med 2021;9:100376.
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Değer et al. (2021) conducted an observational in Chronic Coronary Syndrome (n=142). Gensini score was evaluated on Occurrence of erectile dysfunction (OR 1.06, 95% CI 1.03-1.10, p=<0.001). Every 1 unit increase in the Gensini score was associated with a 6% increase in the occurrence of erectile dysfunction in male patients with chronic coronary syndrome.
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