Key result
Older age, Caucasian ethnicity, high functional class, and multiple comorbidities were associated with higher in-hospital mortality (overall rate 11.2%) in patients hospitalized for heart failure.
Cross-Sectional (n=816)
No
In-hospital mortality for heart failure remains high (11.2%) in this tertiary center, driven by advanced age, severe symptoms, and multiple comorbidities, while baseline ACEi/ARB use is associated with improved survival.
Background: Heart failure is a highly prevalent disease, responsible for many admissions and high mortality rates in our country. The treatment influences patient's mortality and quality of life. Objective: To identify and compare the clinical and epidemiological survivor's and non-survivor's profiles and treatment of patients hospitalized with heart failure with the international literature. Methods: Cross-sectional, retrospective study of 816 survivors and non-survivors with heart failure. All patients had their clinical and epidemiological, laboratory and echocardiographic data and treatment recorded. Results: Most patients were in functional class III/IV. Mean age was 66.5 ± 13.8 years. Half of the patients were men and 88.3% were Caucasians. In-hospital mortality was 11,2%. Highly mortality was associated with old age, Caucasian ethnicity, high functional class, readmissions, prolonged hospitalization, presence of coronary artery disease, chronic atrial fibrillation, severe mitral regurgitation, restrictive diastolic dysfunction, renal dysfunction, and elevated natriuretic peptide levels, as well as with patients who had pulmonary embolism, acute coronary syndrome, pulmonary infection or required dialysis during hospitalization. The use of angiotensin-converting enzyme inhibitors or angiotensin-receptor blockers at admission was significantly higher among survivors. Conclusion: In-hospital mortality was high when compared to international averages, but it was similar to other Brazilian referral services. Numerous higher severity indicators were observed in the non-survivor group.
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Poffo et al. (2017) conducted a cross-sectional in Heart failure (n=816). Older age, Caucasian ethnicity, high functional class, and multiple comorbidities were associated with higher in-hospital mortality (overall rate 11.2%) in patients hospitalized for heart failure.
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