Key result
Review outlines myocardial high-energy phosphate metabolism deficits, 31P MRS assessment, and clinical interpretation.
Why the study?
Deficits in cardiac high-energy phosphate metabolism not secondary to supply-demand mismatch occur in structural heart disease, warranting review of their assessment and interpretation.
How can 31P magnetic resonance spectroscopy be used to non-invasively investigate myocardial energetics in cardiac disease?
How can 31P magnetic resonance spectroscopy be used to non-invasively investigate myocardial energetics in cardiac disease?
This review provides an overview of using 31P magnetic resonance spectroscopy to assess high-energy phosphate metabolism deficits in structural heart disease.
31P-MRS may non-invasively assess myocardial energetics; leaves open prospective validation before clinical adoption in structural heart disease.
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Peterzan et al. (2020) conducted a review in Cardiac disease. 31P magnetic resonance spectroscopy was evaluated. This review outlines the scope of deficits in high-energy phosphate metabolism in the myocardium, their assessment using 31P magnetic resonance spectroscopy, and their clinical interpretation.
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