Population
14 human heart samples: 8 normal human hearts and 6 papillary muscles from patients operated on for mitral…
Design
Cross-sectional
Authors
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CK changes in mitral regurgitation papillary muscle are hypothesis-generating; prospective studies needed before clinical consideration.
Adaptations in the creatine kinase system, including decreased CKMIT and increased CKB, occur in the human heart during disease states like mitral regurgitation, indicating stressed intracellular energy transfer.
Sylvén et al. (1991) studied this question.
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