Key result
Hypertension mortality in older Mississippi adults climbs ~3% annually.
Why the study?
Hypertension rose from the 15th to 11th leading cause of death in Mississippi between 2000 and 2018, but research on temporal trends was limited.
Observational
Hypertension-related mortality has steadily increased among adults aged 45 and older in Mississippi over nearly two decades, highlighting the need for targeted blood pressure lowering interventions.
Rising hypertension mortality among Mississippi adults ≥45 may warrant targeted BP efforts; leaves open causal drivers and intervention efficacy.
BACKGROUND: In Mississippi, hypertension as a leading cause of death moved from 15th in 2000 to 11th in 2018, but research on temporal trends is limited. We examined temporal trends in hypertension-related mortality among Mississippi adults by age, sex, and race. METHODS: We extracted data on the number of deaths due to hypertension among adults aged 45 or older annually from 2000 to 2018 from Mississippi Vital Statistics. We used underlying cause-of-death codes from the International Classification of Diseases, Tenth Revision to identify hypertension deaths. We calculated the annual percentage change (trend segment) and average annual percentage change (AAPC) in age-adjusted hypertension death rates from 2000 to 2018 and examined differences in the AAPC by age, sex, and race. RESULTS: From 2000 through 2018, the age-adjusted hypertension death rate increased annually by 3.0% (AAPC 3.0%, 95% confidence interval, 1.9%-4.0%) with 3 distinct time periods. There was an average annual increase in age-adjusted hypertension death rates for all subgroups, i.e., men, women, Blacks, Whites, White females, Black males, and White males. The highest magnitude of increase was among those aged 45-64 years (AAPC 6.0%), men (AAPC 4.5%), Whites (AAPC 3.5%), and White men (AAPC 6.2%) compared with other age groups, women, Blacks, and Black men, respectively. CONCLUSIONS: For nearly 2 decades, there was an increase in age-adjusted hypertension death rates among Mississippi adults aged 45 years or older. Blood pressure lowering interventions that target hypertensive adults are needed.
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Mendy et al. (2021) conducted an observational in Hypertension. From 2000 to 2018, the age-adjusted hypertension death rate among Mississippi adults aged ≥45 years increased by an average of 3.0% annually (95% CI 1.9%-4.0%).
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