Key result
Age-adjusted US hypertension-related mortality climbs ~36% from 1999 to 2016.
Why the study?
Hypertension-related mortality has been increasing, but limited information exists concerning rate, temporal, secular, and geographic trends in the United States.
Population
Individuals ≥ 35 years of age from CDC death certificate data spanning 1999-2016
Comparison
Trends across age, sex, race, ethnicity, geographic regions, and co-morbidities over time
Design
Observational study using joinpoint regression and proportion testing
Authors
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Accelerating hypertension mortality may warrant renewed BP control emphasis in middle-aged adults; supports further research into post-2011 drivers.
Observational (n=1,079,913)
Effect estimate: 36.4% increase
Absolute Event Rate: 41.84% vs 30.67%
Hypertension-related mortality in the US has accelerated since 2011, particularly among middle-aged and older adults, highlighting a growing public health challenge.
Forrester et al. (2020) conducted an observational in Hypertension-related mortality (n=1,079,913). Time period (1999-2016) vs. 1999 baseline was evaluated on Age-adjusted hypertension-related mortality rate (per 100,000) (36.4% increase). Between 1999 and 2016, the age-adjusted hypertension-related mortality rate in the US increased by 36.4%, with a notable acceleration to a 2.7% average annual increase between 2011 and 2016.
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