Key result
Asthma, especially with β2-mimetic use, was associated with a higher prevalence of tachycardia (3% vs 0.6%; p<0.001) and premature ventricular contractions (4% vs 2%; p=0.03) compared to no asthma.
Why the study?
Does asthma and the use of β2-mimetics increase the risk of cardiac arrhythmias in adult patients?
Population
158 adult patients with a diagnosis of asthma and 6303 participants without asthma from the Utrecht Health…
Comparison
Asthma diagnosis and/or use of β2-mimetics vs Participants without asthma
Design
Cross-sectional
Authors
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May prompt ECG monitoring in asthma patients on β2-mimetics; leaves open causality and outcome impact.
Cross-Sectional (n=6,461)
Does asthma and the use of β2-mimetics increase the risk of cardiac arrhythmias in adult patients?
Adult patients with asthma, especially those treated with β2-mimetics, have a significantly higher prevalence of tachycardia and premature ventricular contractions on resting ECG.
Warnier et al. (2012) conducted a cross-sectional in Asthma (n=6,461). Asthma and β2-mimetics vs. No asthma was evaluated on Any arrhythmia on the ECG (including tachycardia, bradycardia, premature ventricular contraction (PVC), and atrial fibrillation or flutter). Asthma, especially with β2-mimetic use, was associated with a higher prevalence of tachycardia (3% vs 0.6%; p<0.001) and premature ventricular contractions (4% vs 2%; p=0.03) compared to no asthma.
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