Key result
The chest wearable apparatus estimated diastolic, systolic, and mean blood pressure with mean absolute differences of 3.06, 1.83, and 1.80 mmHg compared to a reference cuff-based device.
Why the study?
Does a chest wearable apparatus based on PPG and PCG signals accurately estimate continuous blood pressure compared to a traditional cuff-based device in healthy subjects?
Observational (n=20)
No
Does a chest wearable apparatus based on PPG and PCG signals accurately estimate continuous blood pressure compared to a traditional cuff-based device in healthy subjects?
A novel chest wearable device utilizing PPG and PCG signals can continuously estimate blood pressure with an accuracy comparable to traditional cuff-based devices in healthy subjects.
May support continuous BP monitoring via chest wearables in healthy subjects; leaves open validation in clinical populations.
This paper describes an integrated chest wearable apparatus for continuous blood pressure (BP) measurements exploiting the heart-rate (HR) and the pulse arrival time (PAT) in a modified Moens-Korteweg model. The device embeds a miniaturized gas pressure sensor to record the phonocardiogram (PCG) of the heart sounds, a LED-photodiode pair to detect the photoplethysmogram (PPG) of the blood flow wave, a μcontroller, a wireless communication module and the power supply. With the proposed device no active participation would be required from human subjects for BP measurements, since the HR and the PAT are continuously extracted from the PCG and PPG signals. Dedicated signal processing algorithms were developed and implemented off-line to extract both HR and PAT. A subject-specific calibration protocol of the BP model was designed and implemented. The calibration and validation of the apparatus were performed on a cohort of 20 healthy subjects. A GIMA ABPM pressure Holter was chosen as reference device, and 8 measurements points, evenly distributed over a 10-minute interval, were used for model calibration for each subject. The range of DBP and SBP measurements were 52-85 mmHg and 90-141 mmHg, respectively. The results from Bl- and-Altman analysis showed that the mean±1.96SD for the estimated diastolic, systolic, and mean BP with the proposed method against reference were 0.01±7.55, 1.47±3.76, 0.74±4.38 mmHg, respectively. The corresponding mean absolute differences (MAD) were 3.06, 1.83, and 1.80 mmHg. These results demonstrates that the acquisition apparatus is able to continuously estimate the BP with an accuracy comparable to traditional cuff-based devices.
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Marzorati et al. (2020) conducted an observational in Healthy subjects (n=20). Chest wearable apparatus based on PPG and PCG signals vs. GIMA ABPM pressure Holter was evaluated on Mean absolute difference in estimated blood pressure. The chest wearable apparatus estimated diastolic, systolic, and mean blood pressure with mean absolute differences of 3.06, 1.83, and 1.80 mmHg compared to a reference cuff-based device.
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