Establishment and validation of an extracellular volume model without blood sampling in ST-segment elevation myocardial infarction patients

Figures

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  Figure 1. Workflow.

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  Figure 2. (A) Native T1 map; (B) enhanced T1 map; (C) generated ECV images; and (D) the distribution coefficient λ that generates the image; circles indicate different regions.

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  Figure 3. Linear regression analysis between HCT and blood pool T1.

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  Figure 4. (A) Comparison between conventional HCT and synthetic HCT; (B) comparison between conventional ECV and synthetic ECV in the integral myocardium; (C) comparison between conventional ECV and synthetic ECV in NMIS; and (D) comparison between conventional ECV and synthetic ECV at MIS. NMIS, non-myocardial infarction sites; MIS, myocardial infarction site; ECV, extracellular volume; HCT, haematocrit; ns, not statistically significant.

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  Figure 5. (A) Comparison of conventional ECV between NMIS and MIS in the derivation group; (B) comparison of synthetic ECV between NMIS and MIS in the derivation group; (C) comparison of conventional ECV between NMIS and MIS in the validation group; and (D) comparison of synthetic ECV between NMIS and MIS in the validation group. ***P < 0.001. NMIS, non-myocardial infarction sites; MIS, myocardial infarction site; ECV, extracellular volume; HCT, haematocrit.

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  Figure 6. (A) Comparison between conventional HCT and synthetic HCT; (B) comparison between conventional ECV and synthetic ECV in the integral myocardium; (C) comparison between conventional ECV and synthetic ECV in NMIS; and (D) comparison between conventional ECV and synthetic ECV at MIS. The X-axis represents the mean value. The Y-axis represents bias. The dashed line is mean ± 1.96* SD. NMIS, non-myocardial infarction sites; MIS, myocardial infarction site; ECV, extracellular volume; HCT, haematocrit.

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  Figure 7. (A) Pearson analysis between synthetic HCT and conventional HCT; (B) Pearson analysis between synthetic ECV and conventional ECV in the integral myocardium; (C) Pearson analysis between synthetic ECV and conventional ECV in NMIS; and (D) Pearson analysis between synthetic ECV and conventional ECV in MIS. NMIS, non-myocardial infarction sites; MIS, myocardial infarction site; ECV, extracellular volume; HCT, haematocrit.