Key result
Cytokines modulate myocardial function through complex, bimodal contractile responses, featuring an early variable response followed by a profoundly cardiodepressant late response.
This review highlights the time-dependent and bimodal nature of cytokine-induced myocardial dysfunction, providing a mechanistic framework for understanding cardiac injury and chronic pathologies.
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Alerts to temporal cytokine dynamics in cardiac injury; leaves open targeted interventions pending clinical validation.
Sumanth D. Prabhu (2004) conducted a review in Cardiac diseases. Cytokines was evaluated. Cytokines modulate myocardial function through complex, bimodal contractile responses, featuring an early variable response followed by a profoundly cardiodepressant late response.
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