Resumption of Anticoagulant Therapy in a Severe Trauma Patient with a Mechanical Aortic Valve Replacement

Q: What does this research mean for the field?

Stepwise resumption of heparin and warfarin therapy enables the successful management of mechanical aortic valve replacement patients with severe traumatic intracranial hemorrhage. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

Kanako Mishima; Masato Murata; Makoto Aoki; Masahiko Kanbe; Jun Nakajima; Yusuke Sawada; Yuta Isshiki; Yumi Ichikawa; Kazunori Fukushima; Yuto Aramaki; Keiko Kowase; Jun‐ichi Tamura; Kiyohiro Oshima

doi:10.2974/kmj.69.237

August 1, 2019The Kitakanto Medical JournalOpen Access

Resumption of Anticoagulant Therapy in a Severe Trauma Patient with a Mechanical Aortic Valve Replacement

View Full Paper

Ask AI

Bookmark

Share

Structured PICO

P

Population

1 female in her 60s with a mechanical aortic valve replacement on warfarin therapy who sustained severe trauma (traumatic subarachnoid and subdural hemorrhage, pelvic fracture).

I

Intervention

Resumption of anticoagulant therapy (intravenous heparin followed by oral warfarin) after traumatic hemorrhage.

O

Outcome

Clinical course and safety of anticoagulant resumption (bleeding and thrombotic events).safety

This case report highlights the difficulty of balancing hemostasis and thrombosis when resuming anticoagulation in a patient with a mechanical heart valve who sustains severe traumatic intracranial and pelvic hemorrhage.

Limitations

Single case report
No established criteria for resumption of anticoagulation

Ask about this paper

Answers are grounded in this paper and cite their sources.

Implication

Supports cautious stepwise anticoagulation resumption in select mechanical valve patients with traumatic ICH; hypothesis-generating and requires prospective validation.

Abstract

No abstract yet. The journal hasn't published one we can show.

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Mishima et al. (2019) studied this question.

synapsesocial.com/papers/6a13e4132ecb6dc54189242d https://doi.org/10.2974/kmj.69.237

View Full Paper

Ask AI

Bookmark

Share

Resumption of Anticoagulant Therapy in a Severe Trauma Patient with a Mechanical Aortic Valve Replacement

Structured PICO

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Resumption of Anticoagulant Therapy in a Severe Trauma Patient with a Mechanical Aortic Valve Replacement

Structured PICO

Limitations

Ask about this paper

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading