What does this research mean for the field?

Chronic rheumatic valvular heart disease is present in Iceland, affecting approximately 1.08% of the adult autopsied population, with the majority of cases being undiagnosed prior to death. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.CHALLENGES_CONSENSUS.

What question did this study set out to answer?

To determine the postmortem incidence and clinical recognition of chronic rheumatic valvular heart disease in Iceland.

July 1, 1975Acta Pathologica Microbiologica Scandinavica Section A Pathology

Chronic Rheumatic Valvular Heart Disease

View Full Paper

Ask AI

Bookmark

Population

Autopsies of Icelanders aged 16 years and older who died between November 1965 and December 1974, with a…

Design

Cross-sectional

Authors

JHJónas HallgrímssonHarvard University

Discussion

Member takes

Implication

Autopsy series suggests RHD exists in Iceland; challenges prior doubts and leaves open true prevalence and screening needs.

Key Points

To determine the postmortem incidence and clinical recognition of chronic rheumatic valvular heart disease in Iceland.
Analyzed autopsy records from November 1965 through December 1974, encompassing 28.8% of the approximately 12,400 deaths among individuals aged 16 years and older in Iceland.
Reviewed available hospital records to evaluate prior clinical diagnoses and documented histories of rheumatic fever.
Rheumatic valvular heart disease occurred in 38 subjects (1.08% overall; 0.67% in males and 1.83% in females).
Among hearts presenting chronically deformed valves, rheumatic disease accounted for 20%, whereas calcified aortic stenosis comprised 69%.
Only 18% of affected subjects had a documented history of rheumatic fever, and 71% were diagnosed with rheumatic valvular disease for the first time at autopsy.

Structured PICO

Population

Autopsies of Icelanders aged 16 years and older who died between November 1965 and December 1974 (n=~3,571, representing 28.8% of ~12,400 deaths), with a male to female ratio of 2:1.

Outcome

Incidence of chronic rheumatic valvular heart disease

This autopsy study confirmed the presence of chronic rheumatic valvular heart disease in Iceland, with an incidence of 1.08% among autopsied adults.

Limitations

An evaluation of the functional derangements of the diseased valves was not attempted

Cite This Study

Jónas Hallgrímsson (1975) studied this question.

synapsesocial.com/papers/6a13fb3cc4c5e9e518627ba3 https://doi.org/10.1111/j.1699-0463.1975.tb01391.x

Topics

Valvular heart disease

View Full Paper

Ask AI

Bookmark

Chronic Rheumatic Valvular Heart Disease

Discussion

Member takes

Implication

Key Points

Structured PICO

Limitations

Cite This Study

Topics

Chronic Rheumatic Valvular Heart Disease

Discussion

Member takes

Implication

Key Points

Structured PICO

Limitations

Cite This Study

Also Consider

Topics

Also Consider