Key result
Young adults with isolated systolic hypertension had a 50% slower rate of receiving a hypertension diagnosis (HR 0.50) compared to those with combined systolic/diastolic hypertension.
Why the study?
Do diagnosis and treatment rates differ between isolated systolic, isolated diastolic, and combined systolic/diastolic hypertension in young adults?
Observational (n=3,003)
No
Do diagnosis and treatment rates differ between isolated systolic, isolated diastolic, and combined systolic/diastolic hypertension in young adults?
Young adults with isolated systolic hypertension experience significantly slower rates of clinical diagnosis and medication initiation compared to those with combined systolic/diastolic hypertension, highlighting a potential gap in care.
May signal care gaps for young adults with isolated systolic hypertension; leaves open whether targeted screening improves outcomes.
Differential rates of diagnosis and treatment by hypertension (HTN) type may contribute to poor HTN control in young adults. The objective of this study was to compare rates of receiving a hypertension diagnosis and antihypertensive agent among young adults with (1) isolated systolic, (2) isolated diastolic, and (3) combined systolic/diastolic HTN. A retrospective analysis was conducted in patients aged 18 to 39 years (n=3003) with incident HTN. Kaplan-Meier survival and Cox proportional hazards analyses were performed. Only 56% with isolated systolic HTN received a diagnosis compared with 63% (systolic/diastolic); 32% with isolated systolic HTN received an initial antihypertensive compared with 52% (systolic/diastolic). Compared with patients with systolic/diastolic HTN, those with isolated systolic HTN had a 50% slower diagnosis rate (hazard ratio [HR], 0.50; 95% confidence interval [CI], 0.41-0.60) and those with isolated diastolic HTN had a 26% slower rate (HR, 0.74; CI, 0.60-0.92). Patients with isolated systolic HTN had 58% slower medication initiation (HR, 0.42; CI, 0.34-0.51) and those with isolated diastolic HTN had 31% slower rates (HR, 0.69; CI, 0.55-0.86). Young adults with isolated systolic HTN have lower diagnosis and treatment rates.
No takes yet. Share an insight, caveat, or question.
Johnson et al. (2015) conducted an observational in Incident Hypertension (n=3,003). Isolated systolic hypertension vs. Combined systolic/diastolic hypertension was evaluated on Time to initial hypertension diagnosis (HR 0.50, 95% CI 0.41-0.60, p=<0.001). Young adults with isolated systolic hypertension had a 50% slower rate of receiving a hypertension diagnosis (HR 0.50) compared to those with combined systolic/diastolic hypertension.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: