February 19, 2009American Journal of HypertensionOpen Access

Natural History of Hypertension Subtypes in Young and Middle-Age Adults

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Why the study?

Does the subtype of stage 1 hypertension in young-to-middle-age adults predict the risk of developing sustained hypertension?

Population

1,141 participants aged 18-45 years screened for stage 1 hypertension, and 101 nonhypertensive control…

Comparison

Stage 1 hypertension subtypes vs Nonhypertensive control subjects and comparison…

Design

Cohort

Follow-up

median 72.9 months

Authors

FSFrancesca SaladiniPreventive Cardiology FDFrancesca DorigattiUniversity of Padua MSMassimo SantonastasoOspedale Civile di Vittorio Veneto

Discussion

Member takes

Implication

ISH in young adults linked to lower sustained HT risk than IDH/SDH; leaves open subtype-specific monitoring strategies pending prospective validation.

Structured PICO

Does the subtype of stage 1 hypertension in young-to-middle-age adults predict the risk of developing sustained hypertension?

Population

1,141 participants aged 18-45 years screened for stage 1 hypertension, and 101 nonhypertensive control subjects from the HARVEST study.

Intervention

Stage 1 hypertension subtypes (isolated systolic hypertension [ISH], isolated diastolic hypertension [IDH], systolic-diastolic hypertension [SDH])

Comparator

Nonhypertensive control subjects and comparison between hypertension subtypes

Outcome

Development of sustained hypertension (clinic blood pressure >=140/90 mm Hg from two consecutive visits occurring at least after >=6 months of observation) or ambulatory hypertension (mean daytime blood pressure >=135/85 mm Hg)surrogate

Young-to-middle-age adults with isolated systolic hypertension have a lower risk of progressing to sustained ambulatory hypertension compared to those with isolated diastolic or systolic-diastolic hypertension.

Cite This Study

Saladini et al. (2009) studied this question.

synapsesocial.com/papers/6a7e2251c82fecdb5194e446 https://doi.org/10.1038/ajh.2009.21

Topics

Hypertension management

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Implication

ISH in young adults linked to lower sustained HT risk than IDH/SDH; leaves open subtype-specific monitoring strategies pending prospective validation.