Key result
The interaction between greater depressive symptoms and decreased global cerebral blood flow velocity was associated with greater deficits in attention/executive function (β = 0.32, p = 0.003).
Why the study?
Does cerebral perfusion moderate the association between depressive symptoms and cognitive impairment in older adults with heart failure?
Cross-Sectional (n=89)
Does cerebral perfusion moderate the association between depressive symptoms and cognitive impairment in older adults with heart failure?
Effect estimate: β = 0.32
p-value: p=0.003
Depressive symptoms and cerebral hypoperfusion interact to adversely affect cognitive performance, specifically attention and executive function, in older adults with heart failure.
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Hypothesis-generating for perfusion-depression interplay in HF cognition; leaves open need for longitudinal and interventional studies.
Alosco et al. (2013) conducted a cross-sectional in Heart failure (n=89). The interaction between greater depressive symptoms and decreased global cerebral blood flow velocity was associated with greater deficits in attention/executive function (β = 0.32, p = 0.003).
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