Key result
A function of systolic blood pressure variability and average diastolic pressure predicted total white matter hyperintensities in older adults with cardiovascular disease.
Why the study?
Is blood pressure variability associated with white matter hyperintensities in older adults with cardiovascular disease?
Cross-Sectional (n=39)
Is blood pressure variability associated with white matter hyperintensities in older adults with cardiovascular disease?
Blood pressure variability is an important contributor to white matter hyperintensities in older adults with cardiovascular disease, with differential relationships across brain regions.
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No immediate practice change; leaves open whether targeting systolic variability reduces white matter hyperintensities in older adults with cardiovascular disease.
Gunstad et al. (2005) conducted a cross-sectional in Cardiovascular disease (n=39). Blood pressure variability was evaluated on White matter hyperintensities (WMH) in neocortical, periventricular and subcortical brain regions. A function of systolic blood pressure variability and average diastolic pressure predicted total white matter hyperintensities in older adults with cardiovascular disease.
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