Key result
Angiotensin II plays a key role in regulating proximal tubular functions through the recently identified intrarenal renin-angiotensin system.
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Design
Review
May inform tubular physiology research; leaves open clinical translation of intrarenal RAS targeting.
Recent studies have revealed the existence of intrarenal renin-angiotensin system and broadened our understanding on the role of angiotensin II in the regulation of proximal tubular functions. The aims of the present review are to summarize these recent findings and to highlight new questions that have arisen therefrom.
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Norimoto Yanagawa (1998) studied this question. Angiotensin II plays a key role in regulating proximal tubular functions through the recently identified intrarenal renin-angiotensin system.
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