Key result
The intratubular renin-angiotensin system plays a key role in the pathophysiology of hypertension and serves as a target for pharmacological blockade.
This review highlights the role of the intratubular renin-angiotensin system in hypertension pathophysiology and its response to pharmacological blockade.
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May inform RAS inhibitor choice in hypertension; extends local renal mechanisms but leaves open targeted trial confirmation.
Suzaki et al. (2006) conducted a review in Hypertension. Renin-angiotensin system blockade was evaluated. The intratubular renin-angiotensin system plays a key role in the pathophysiology of hypertension and serves as a target for pharmacological blockade.
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