Personal reflections on efforts to reduce ischemic myocardial damage
Key result
Ligation of a major coronary artery in dogs was observed by 19th-century physiologists to be immediately fatal, contributing to early research on acute myocardial infarction.
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Discussion
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Implication
Anchors current time-sensitive AMI care in early fatal observations; extends 19th-century physiology to reperfusion-era trials.
Key Points
Key points are not available for this paper at this time.
Cite This Study
Eugene Braunwald (2002) studied this question. Ligation of a major coronary artery in dogs was observed by 19th-century physiologists to be immediately fatal, contributing to early research on acute myocardial infarction.