Kidney function and risk of cardiovascular disease and mortality in women: a prospective cohort study
Authors
Discussion
Loading...
Member takes
Implication
Prospective cohort study finds kidney function impacts cardiovascular disease mortality in women, suggesting health monitoring is essential.
Key Points
- To evaluate the link between kidney function and cardiovascular disease and mortality in women.
- Conducted a prospective cohort study with 27,939 female health professionals aged 45 and older.
- Measured glomerular filtration rate at study entry and monitored cardiovascular disease events and mortality over 12 years.
- Confirmed outcomes through medical records and death certificates.
- Women with GFR <60 ml/min/1.73 m² had an increased risk of cardiovascular disease death (hazard ratio 1.68, 95% CI 1.02 to 2.79).
- No significant changes in risk for other cardiovascular events were found among women with less severe kidney impairment.
- Adjusted hazard ratios for first cardiovascular disease events were close to 1 for different GFR categories, indicating a lack of association.
Cite This Study
Kurth et al. (2009) studied this question.