Why the study?
Does age and sodium intake affect plasma and atrial ANF levels in rats?
Population
Young (2 mo), mature (4 mo), and older adult (12-18 mo) rats maintained on a low-sodium diet for 8 days
Comparison
High-sodium diet (3.1%) for 24 hours vs Continued low-sodium diet
Design
Preclinical
Follow-up
9 days
Authors
Loading...
May modulate cardiovascular homeostasis in aging rats; leaves open translation to human ANF changes or clinical relevance.
Does age and sodium intake affect plasma and atrial ANF levels in rats?
Plasma and atrial ANF levels increase with age in rats, suggesting that increased ANF effects may modulate cardiovascular homeostasis during aging.
Korytkowski et al. (1991) studied this question.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: