September 8, 2010Catheterization and Cardiovascular Interventions
Assessment of the aortic annulus by multislice computed tomography, contrast aortography, and trans‐thoracic echocardiography in patients referred for transcatheter aortic valve implantation
Key result
Aortic annulus dimensions differed significantly across MSCT, contrast aortography, and TTE, with MSCT demonstrating substantially lower interobserver variability (r=0.95) than TTE and CA.
Why the study?
What is the level of agreement and reproducibility among MSCT, CA, and TTE for measuring the aortic annulus in patients referred for TAVI?
Population
70 patients with severe aortic stenosis referred for Transcatheter Aortic Valve Implantation (TAVI)
Comparison
Multislice computed tomography and contrast… vs Trans-thoracic echocardiography (TTE)
Design
Cross-sectional
Authors
Discussion
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Implication
MSCT offers superior reproducibility for aortic annulus sizing; leaves open which modality optimizes TAVI outcomes.
Study Design
Type
Cross-Sectional (n=70)
Structured PICO
What is the level of agreement and reproducibility among MSCT, CA, and TTE for measuring the aortic annulus in patients referred for TAVI?
P
Population
70 patients with severe aortic stenosis referred for Transcatheter Aortic Valve Implantation (TAVI)
I
Intervention
Multislice computed tomography (MSCT) and contrast aortography (CA)
C
Comparator
Trans-thoracic echocardiography (TTE)
O
Outcome
Level of agreement and reproducibility (interobserver variability) of aortic annulus dimensionssurrogate
MSCT provides highly reproducible measurements of the aortic annulus compared to TTE and CA, though absolute measurements differ significantly between the imaging modalities.
Cite This Study
Tzikas et al. (2010) conducted a cross-sectional in Severe aortic stenosis (n=70). Multislice computed tomography (MSCT) vs. Contrast aortography (CA) and trans-thoracic echocardiography (TTE) was evaluated on Agreement between imaging techniques and interobserver variability for aortic annulus dimensions. Aortic annulus dimensions differed significantly across MSCT, contrast aortography, and TTE, with MSCT demonstrating substantially lower interobserver variability (r=0.95) than TTE and CA.