Key result
The incidence of VT/VF in STEMI patients undergoing PPCI was 11%, and a newly developed risk assessment model predicted its occurrence with an area under the curve of 0.88.
Why the study?
VT/VF is a malignant arrhythmia in STEMI patients receiving PPCI, but risk assessment tools to anticipate its occurrence were lacking.
What are the risk factors and can a risk assessment model predict the occurrence of VT/VF in STEMI patients undergoing PPCI?
Observational (n=607)
No
What are the risk factors and can a risk assessment model predict the occurrence of VT/VF in STEMI patients undergoing PPCI?
May aid early monitoring in STEMI; leaves open prospective validation of the model.
Ventricular tachycardia/ventricular fibrillation (VT/VF) is a kind of malignant arrhythmia in ST-segment elevation myocardial infarction (STEMI) patients who received primary percutaneous coronary intervention (PPCI). However, there are no risk assessment tools to anticipate the occurrence of VT/VF.This study is to build a risk assessment model to predict the possibility of VT/VF onset in STEMI patients undergoing PPCI.A retrospective study was conducted to analyze the patients who underwent PPCI from January 2006 to May 2015. Subjects were divided into VT/VF group and no VT/VF group based on whether VT/VF had occurred or not. In addition, the VT/VF group was further separated into early-onset group (from the time that symptoms began to before the end of PPCI) and late-onset group (after the end of PPCI) based on the timing of when VT/VF happened. Multivariate regression analysis was carried out to distinguish the independent risk factors of VT/VF and an additional statistical method was executed to build the risk assessment model.A total of 607 patients were enrolled in this study. Of these patients, 67 cases (11%) experienced VT/VF. In addition, 91% (61) of patients experienced VT/VF within 48 h from the time that the symptoms emerged. Independent risk factors include: age, diabetes mellitus, heart rate, ST-segment maximum elevation, ST-segment total elevation, serum potassium, left ventricular ejection fraction (LVEF), culprit artery was right coronary artery, left main (LM) stenosis, Killip class > I class, and pre-procedure thrombolysis in myocardial infarction (TIMI) flow zero grade. Risk score model and risk rank model have been established to evaluate the possibility of VT/VF. Class I: ≤ 4 points; Class II: > 4 points, ≤ 5.5 points; Class III: > 5.5 points, < 6.5 points; and Class IV ≥ 6.5 points. The higher the class, the higher the risk.The incidence of VT/VF in STEMI patients undergoing PPCI is 11% and it occurs more frequently from the time that symptoms begin to before the end of PPCI, which, in most cases, occurs within 48 h of the event. Our risk assessment model could predict the possible occurrence of VT/VF.
No takes yet. Share an insight, caveat, or question.
Huang et al. (2019) conducted an observational in ST-segment elevation myocardial infarction (STEMI) (n=607). Risk assessment model was evaluated on Incidence of ventricular tachycardia or ventricular fibrillation (VT/VF). The incidence of VT/VF in STEMI patients undergoing PPCI was 11%, and a newly developed risk assessment model predicted its occurrence with an area under the curve of 0.88.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: